Dysphoria and impulsivity are states that are described across a range of psychiatric disorders. However, current diagnostic systems like the DSM and ICD, along with traditional psychiatric literature, often overlook the subtle, embodied nuances of these phenomena. The reliance on standardized psychometric scales and efficacy-based guidelines in choosing medication circumvents a more personalized approach within a phenomenological framework that integrates clinical judgment with a deep understanding of patients’ embodied experiences. This paper proposes a phenomenologically informed approach in relation to understanding and targeting dysphoria and impulsivity in pharmacological interventions. While one may be inclined to use a specific medication based on label information, the effect on a person’s embodied experience can vary significantly. Additionally, the same medication may change the experience of impulsivity or dysphoria in one person in a completely different manner than in another person, which raises the possibility that medications may have their own “phenomenological profiles”. Another important aspect is the role of intersubjectivity in the clinician-patient relationship. By modulating the patient’s affective responses and facilitating a more balanced sense of self, medication might allow for a deeper, clearer articulation of their lived experience during clinical encounters. Ultimately, I argue for a more nuanced, phenomenologically informed approach to pharmacological intervention. Integrating the patient’s lived, embodied experience with an understanding of the subtle effects of medication can enhance clinical judgment and potentially lead to more effective, personalized treatments.